Description
NEDD8 Antibody | F42040-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This NEDD8 antibody is available for research use only.
Purity: Purified
Description: NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Immunogen: A portion of amino acids 1-32 from the human protein was used as the immunogen for this NEDD8 antibody.
Storage: Aliquot the NEDD8 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
