NAMPT Polyclonal Antibody | E-AB-40013

NAMPT Polyclonal Antibody | E-AB-40013 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Cardiovascular, Metabolism, Immunology, Neuroscience, Signaling transduction

Background: Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Lead Time: 7~10 days

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Nicotinamide phosphoribosyltransferase protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification: Affinity purification

Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 56 kDa

Observed Molecular Weight: N/A

Clonality: Polyclonal