Description
MYOZ2 Polyclonal Antibody | E-AB-18659 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: IHC, ELISA
Research Area: Cardiovascular, Signal Transduction
Background: MYOZ2 (Myozenin 2) is a Protein Coding gene. Diseases associated with MYOZ2 include Cardiomyopathy, Hypertrophic, 16 and Myoz2-Related Familial Hypertrophic Cardiomyopathy. GO annotations related to this gene include actin binding and telethonin binding. An important paralog of this gene is MYOZ1.The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
Lead Time: 7~10 days
Concentration: 1.32 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Full length fusion protein
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: Polyclonal
