Description
Myoglobin Antibody | R30924 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This Myoglobin antibody is available for research use only.
Purity: Antigen affinity
Description: Myoglobin (MB) also known as PVALB, is a single-chain globular protein of 153 or 154 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. Two structural variants of myoglobin were described by Boyer et al.(1963). Boulton et al.(1969) studied postmortem muscle from 2,500 people. Two Myoglobin variants were found, and in one of these substitution of lysine for glutamic acid at residue 53 was demonstrated. MG was the first protein to have its three-dimensional structure revealed. Jeffreys et al.(1984) used DNA probes isolated from the cloned gene to map the gene in human-rodent somatic cell hybrids. The locus mapped to chromosome 22q11-q13. MG is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations. The released MG is filtered by the kidneys but is toxic to the renal tubular epithelium and so may causeacute renal failure.
Immunogen: An amino acid sequence from the C-terminus of human Myoglobin (LFRKDMASNYKELGFQG) was used as the immunogen for this Myoglobin antibody.
Storage: After reconstitution, the Myoglobin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
