MYD88 Polyclonal Antibody | E-AB-64029

MYD88 Polyclonal Antibody | E-AB-64029 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Cardiovascular, Immunology, Signal Transduction

Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human MYD88 (NP_002459.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 15 kDa/20 kDa/28 kDa/31 kDa/33 kDa/34 kDa

Observed Molecular Weight: 37 kDa

Clonality: N/A