MUC18 / Mucin 18 / CD146(OJ79c), 1mg/mL Antibody | BNUM0676-50

MUC18 / Mucin 18 / CD146(OJ79c), 1mg/mL Antibody | BNUM0676-50| Gentaur Distribution US, UK & Europe

Summary.: The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: Purified, BSA-free.

Storage Buffer: PBS, no BSA, no azide.

Storage Temperature: 35°C to -5°C .

Application: Flow, surface (published)|IF (published)|ELISA (published).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.