MUC1 Antibody / Mucin-1 | V9048-100UG

MUC1 Antibody / Mucin-1 | V9048-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: SPM533

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Mucin-1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Mucin-1 is a 265-400kDa glycoprotein. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit and the C-terminal beta subunit. . The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. MUC1 may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions.

Immunogen: Delipidated extract of human milk fat globule membranes was used as the immunogen for this Mucin-1 antibody.

Storage: Store the Mucin-1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).