MUC1 Antibody / Mucin-1 | V8931-100UG

MUC1 Antibody / Mucin-1 | V8931-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: Mc5

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB, IHC-P

Buffer: N/A

Limitation: This MUC1 antibody is available for research use only.

Purity: Protein A/G affinity

Description: The mucin antigen recognized by Mc-5 is a glycosylated molecule with a molecular mass of 400 kD. The sequence to which this antibody binds is Thr-Arg-Pro-Ala-Pro. Although EMA is primarily located in mammary gland epithelium, other normal epithelia (e.g., lung) will also react against EMA antibody. Staining, however, is the strongest in mammary epithelia. The combination of positive staining for keratin with negative EMA can be used to phenotype the above-mentioned epithelial tumors. Recognizes the mucin antigen that is present in most epithelial tissues (breast, colonic, bronchial, gastric, etc.) This antibody does not recognize myelopoietic, lymphopoietic, fibroblasts or sarcomatous cells.

Immunogen: Delipidated human milk fat globules were used as the immunogen for the MUC1 antibody. The sequence to which this antibody binds is Thr-Arg-Pro-Ala-Pro.

Storage: Aliquot the MUC1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.