MUC1 Antibody / Mucin-1 | V7967SAF-100UG

MUC1 Antibody / Mucin-1 | V7967SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: VU-11D1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA

Buffer: N/A

Limitation: This MUC1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: MAb VU-11D1 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of MAb VU-11D1 is the 7-mer TSAPDTR of the MUC1 tandem repeat as established with 'epitope fingerprinting'. The'extra cellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.

Immunogen: Human breast cancer cell line ZR-75 cells were used as the immunogen for this MUC1 antibody.

Storage: Store the MUC1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).