Description
mTOR Antibody (FRAP1) | F49548-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, IF, ELISA
Buffer: N/A
Limitation: This mTOR antibody is available for research use only.
Purity: Antigen affinity
Description: FRAP1/mTOR belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. It is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Immunogen: A portion of amino acids 2459-2488 from the human protein was used as the immunogen for this mTOR antibody.
Storage: Aliquot the mTOR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
