MT2-MMP Antibody / MMP15 | RQ6328

MT2-MMP Antibody / MMP15 | RQ6328 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, IF, FACS, Direct ELISA

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This MT2-MMP antibody is available for research use only.

Purity: Antigen affinity purified

Description: Matrix metalloproteinase 15 (MMP15) also known as Membrane-type-2 matrix metalloproteinase (MT2-MMP) is an enzyme that in humans is encoded by the MMP15 gene. This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression.

Immunogen: Recombinant human protein (amino acids Y132-A202) was used as the immunogen for the MT2-MMP antibody.

Storage: After reconstitution, the MT2-MMP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.