MSSK1 (SRPK3), GST-tag | 40132
- SKU:
- 412-40132
Description
MSSK1 (SRPK3), GST-tag | 40132 | Gentaur US, UK & Europe Disrtribition
Category: Kinase-Serine/Threonine/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: MSSK1, also known as SRPK3, is a muscle-specific protein kinase belonging to the serine arginine protein kinase family which phosphorylates serine/arginine repeat-containing proteins. Heart and skeletal muscle show high expression of the MSSK1/SRPK3 gene product. SRPK3-null mice display a new entity of type 2 fiber-specific myopathy with a marked increase in centrally placed nuclei. Transgenic mice overexpressing SRPK3 in skeletal muscle show severe myofiber degeneration and early lethality (1).
Description: Recombinant human MSSK1 (SRPK3), full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
Product Type: Protein
Shippement Condition: -80°C
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