MSK1 Antibody (pS376) | RQ4786

MSK1 Antibody (pS376) | RQ4786 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: FCF-18

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This phospho-MSK1 antibody is available for research use only.

Purity: Affinity purified

Description: 'Mitogen and stress activated protein kinase 1,' also called RPS6KA5, is a serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. [UniProt]

Immunogen: A synthetic peptide specific to human MSK1 / RPS6KA5 (surrounding pS376) was used as the immunogen for the phospho-MSK1 antibody.

Storage: Store the phospho-MSK1 antibody at -20 °C.