Description
Mouse Siglec-15 / CD33L3 Protein, His Tag | SG5-M52H7-100ug| Gentaur Distribution US, UK & Europe
Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig) -like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
Source: Mouse Siglec-15, His Tag (SG5-M52H7) is expressed from human 293 cells (HEK293). It contains AA Arg 24 - Thr 262 (Accession # A7E1W8-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Arg 24 - Thr 262.
Conjugate: Unconjugated.
Molecular Weight: 27.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.5 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS with Arginine, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
