Description
Mouse Siglec-10 Protein, His Tag | SI0-M52H7-100ug| Gentaur Distribution US, UK & Europe
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
Source: Mouse Siglec-10, His Tag (SI0-M52H7) is expressed from human 293 cells (HEK293). It contains AA Met 18 - Lys 543 (Accession # Q80ZE3-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Met 18 - Lys 543.
Conjugate: Unconjugated.
Molecular Weight: 60.7 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.7 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 25 mM MES, 150 mM NaCl, pH5.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
