Mouse IL-6 Antibody, Mouse IgG1 (1A11E2) | IL6-Y65-1mg

Mouse IL-6 Antibody, Mouse IgG1 (1A11E2) | IL6-Y65-1mg| Gentaur Distribution US, UK & Europe

Interleukin 6 (IL-6) is also known as HGF, BSF2, HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages, monocytes, fibroblasts, endothelial cells, et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic, lupus erythematosus, prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.

Source: Mouse ILN/A6 Antibody, Mouse IgG1 (1A11E2) is a chimeric monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which combines the variable region of a mouse monoclonal antibody with mouse IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and BN/Alymphocytes obtained from a mouse immunized with ILN/A6.

Molecule: ILN/A6.

Species: Mouse.

Tag: Mouse IgG1 | kappa.

Conjugate: Unconjugated.

Purity: N/A.

Charactirization: N/A.

Storage Conditions: -20℃.

Shipping Conditions: RT