Description
Mouse IgG2b Fc Protein, Tag Free (MALS verified) | IGB-M5203-1mg| Gentaur Distribution US, UK & Europe
Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F (ab) s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
Source: Mouse IgG2b Fc, Tag Free (IGB-M5203) is expressed from human 293 cells (HEK293). It contains AA Glu 97 - Lys 335 (Accession # P01867-2).
Format: Powder.
Tag: Native.
Expression System: HEK293.
Expression Region: Glu 97 - Lys 335.
Conjugate: Unconjugated.
Molecular Weight: 26.7 kDa.
Characteristics: This protein carries no "tag". The protein has a calculated MW of 26.7 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
