Description
Mouse GM-CSF R alpha Protein, His Tag | GMA-M52H3-1mg| Gentaur Distribution US, UK & Europe
GM-CSF R alpha (Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.
Source: Mouse GM-CSF R alpha Protein, His Tag (GMA-M52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 30 - Pro 327 (Accession # NP_034100.2).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Leu 30 - Pro 327.
Conjugate: Unconjugated.
Molecular Weight: 34.1 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.1 kDa. The protein migrates as 45-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
