Description
Mouse GITR / TNFRSF18 Protein, His Tag | GIR-M5220-1mg| Gentaur Distribution US, UK & Europe
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Source: Mouse GITR, His Tag (GIR-M5220) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - His 153 (Accession # Q8C4K3).
Format: Powder.
Tag: C-8×His.
Expression System: HEK293.
Expression Region: Ser 22 - His 153.
Conjugate: Unconjugated.
Molecular Weight: 15.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.5 kDa. The protein migrates as 27-34 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT