Description
Mouse CDNF Protein, His Tag (MALS verified) | CDF-M52H3-50ug| Gentaur Distribution US, UK & Europe
CDNF is a member of the ARMET family and acts as a trophic factor for dopamine neurons. CDNF inhibits the 6-hydroxydopamine (6-OHDA) -induced degeneration of dopaminergic neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the dopaminergic function and inhibits the degeneration of dopaminergic neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum.
Source: Mouse CDNF, His Tag (CDF-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Leu 187 (Accession # Q8CC36).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gln 25 - Leu 187.
Conjugate: Unconjugated.
Molecular Weight: 20.4 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.4 kDa. The protein migrates as 21-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
