Description
Mouse CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified) | CD1-M53H3-500ug| Gentaur Distribution US, UK & Europe
CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.
Source: Mouse CD39L1 / ENTPD2 Protein, His Tag (CD1-M53H3) is expressed from CHO cells. It contains AA Cys 26 - Ser 462 (Accession # O55026-1).
Format: Liquid.
Tag: C-10×His.
Expression System: CHO.
Expression Region: Cys 26 - Ser 462.
Conjugate: Unconjugated.
Molecular Weight: 50.2 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.2 kDa. The protein migrates as 44-46 kDa and 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 20mM Tris, 150mM NaCl, pH7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
