Description
Mouse CD3 epsilon&CD3 delta Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (MALS verified) | CDD-M52W2-1mg| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: Mouse CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag (CDD-M52W2) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Asp 108 (CD3E) & Phe 22 - Ala 105 (CD3D) (Accession # P22646-1 (CD3E) & P04235-1 (CD3D) ).
Format: Powder.
Tag: C-Fc & C-10×His | C-Fc & C-Flag.
Expression System: HEK293.
Expression Region: Asp 23 - Asp 108 (CD3E) & Phe 22 - Ala 105 (CD3D).
Conjugate: Unconjugated.
Molecular Weight: 41.5 kDa (CD3E) & 40.7 kDa (CD3D).
Characteristics: Mouse CD3E&CD3D Heterodimer Protein, Fc, His Tag&Fc, Flag Tag is produced by co-expression of CD3E and CD3D, has a calculated MW of 41.5 kDa (CD3E) and 40.7 kDa (CD3D). Subunit CD3E is fused with a human IgG1 Fc tag and a polyhistidine tag at the C-terminus and subunit CD3D is fused with a human IgG1 Fc tag and a flag tag at the C-terminus. As a result of glycosylation, the heterodimer protein migrates as 55-65 kDa under reducing (R) condition, and 90-116 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity: 95%.
Buffer: 50 mM Tris, 100mM Glycine, 25mM Arginine, 150mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
