Description
Monoclonal Anti-DM-1 Antibody, Mouse IgG1 (MALS verified) | DM1-Y73-1mg| Gentaur Distribution US, UK & Europe
Mertansine (DM-1) is a tubulin inhibitor that binds to the ends of microtubules and inhibits microtubule dynamics. DM-1 (Mertansine) has antitumor activity and functions as a regulator of tubulin. It is an alpha-amino acid ester, a carbamate, an epoxide, an organic heterocyclic tetracyclic compound, an organochlorine compound, a mercaptan, and a maydenin alkaloid. DM-1, derived from Mydenin, is a cytotoxic component of antibody-drug conjugations that produce antibody-drug conjugations via a sulfhydryl group splice with SPP (n-succinimide 4- (2-pyridyl dithio) ) or SMCC (4- (3-mercapto-2, 5-dioxy-1 pyrrolidyl) -cyclohexanic acid) splice.
Source: Mertansine (DMN/A1) is a tubulin inhibitor that binds to the ends of microtubules and inhibits microtubule dynamics. DMN/A1 (Mertansine) has antitumor activity and functions as a regulator of tubulin. It is an alphaN/Aamino acid ester, a carbamate, an epoxide, an organic heterocyclic tetracyclic compound, an organochlorine compound, a mercaptan, and a maydenin alkaloid. DMN/A1, derived from Mydenin, is a cytotoxic component of antibodyN/Adrug conjugations that produce antibodyN/Adrug conjugations via a sulfhydryl group splice with SPP (nN/Asuccinimide 4N/A (2N/Apyridyl dithio) ) or SMCC (4N/A (3N/AmercaptoN/A2, 5N/AdioxyN/A1 pyrrolidyl) N/Acyclohexanic acid) splice.
Molecule: DMN/A1.
Species: Mouse.
Tag: Mouse IgG1 | Mouse Kappa.
Conjugate: Unconjugated.
Purity: 95%.
Charactirization: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
