Description
MNK1 Kinase Assay Kit | 78032 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Assay Kit
Application: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: MAPK-interacting serine/threonine-protein kinase 1 (MNK1) is a member of the serine/threonine family that plays a role in mitotic cell cycle progression. Alteration of MNK1 has been shown in various cancers such as breast carcinoma and melanoma. MNK1 phosphorylates eukaryotic translation initiation factor 4E (eIF4E), enhancing phosphorylation of quiescent cells and rendering eIF4E oncogenic.
Description: The MNK1 Kinase Assay Kit is designed to measure MNK1 kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.
Product Type: Assay Kit
Shippement Condition: -80°C