Description
MMP7 Antibody | R31468 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P, ELISA
Buffer: N/A
Limitation: This MMP7 antibody is available for research use only.
Purity: Antigen affinity
Description: Matrix metalloproteinase-7, previously called putative metalloproteinase I (PUMP1) or Matrilysin, has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. It is a mediator of pulmonary fibrosis and a potential therapeutic target.
Immunogen: Human partial recombinant protein (AA 1-267) was used as the immunogen for this MMP7 antibody.
Storage: After reconstitution, the MMP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
