MMP7 Antibody | F49501-0.08ML

MMP7 Antibody | F49501-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, IF, ELISA

Buffer: N/A

Limitation: This MMP7 antibody is available for research use only.

Purity: Purified

Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Immunogen: A portion of amino acids 117-146 from the human protein was used as the immunogen for this MMP7 antibody.

Storage: Aliquot the MMP7 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.