MMP3 (K45E) FluorogenicAssay Kit | 79907

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SKU:
412-79907
Weight:
1.00 KGS
€1,096.00
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Description

MMP3 (K45E) FluorogenicAssay Kit | 79907 | Gentaur US, UK & Europe Disrtribition

Category: Protease/Protein

Application: Great for studying enzyme kinetics and screening small molecule inhibitors and antibodies for drug discovery and HTS applications.

Background: Matrix metalloproteinase 3 (MMP3) is a zinc-dependent endopeptidase involved in the breakdown of extracellular matrix and tissue remodeling in normal physiological processes, such as embryonic development and reproduction, as well as in disease processes, such as arthritis and cancer. Overexpression of MMPs is associated with tumor invasion, neoangiogenesis and metastasis. Several inhibitors of MMPs (MMPI), small molecules and blocking monoclonal antibodies, have entered clinical trials. MMP3 (K45E) variant is associated with differences in MMP3 activity and has been linked to cancer susceptibility.

Description: The MMP3 (K45E) Inhibitor Screening Assay Kit is designed to measure the endopeptidase activity of MMP3 (K45E) for screening and profiling applications. 

Product Type: Assay Kit

Shippement Condition: -80°C

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