Description
MMP2 Polyclonal Antibody | E-AB-40410 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cardiovascular, Cancer, Cell Biology, Metabolism
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
Lead Time: 7~10 days
Concentration: 0.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Rat 72 kDa type IV collagenase protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Purification: Antigen Affinity Purification
Dilution: WB 1:500-1:2000 IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 74 kDa
Observed Molecular Weight: 74 kDa
Clonality: Polyclonal
