Description
MMP14 Antibody | F54844-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, FACS, IHC-P
Buffer: N/A
Limitation: This MMP14 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.
Immunogen: A portion of amino acids 145-174 from the human protein was used as the immunogen for the MMP14 antibody.
Storage: Aliquot the MMP14 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
