Description
MMP14 Antibody | F40218-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 133CT15.10.5.1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IF, ELISA
Buffer: N/A
Limitation: This MMP14 antibody is available for research use only.
Purity: Purified
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Immunogen: A portion of amino acids 470-499 from the human protein was used as the immunogen for this MMP14 antibody.
Storage: Aliquot the MMP14 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
