Description
MMP11 Polyclonal Antibody | E-AB-15781 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Cell Biology, Cardiovascular, Signal Transduction
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
Lead Time: 7~10 days
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human MMP11
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 55 kDa
Observed Molecular Weight: N/A
Clonality: Polyclonal
