Description
MLH1 Antibody | F41625-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, ELISA
Buffer: N/A
Limitation: This MLH1 antibody is available for research use only.
Purity: Antigen affinity
Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Immunogen: A portion of amino acids 452-480 from the human protein was used as the immunogen for this MLH1 antibody.
Storage: Aliquot the MLH1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
