MGMT Antibody | F52339-0.4ML

MGMT Antibody | F52339-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 888CT22.2.4

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC, IF, WB, ELISA

Buffer: N/A

Limitation: This MGMT antibody is available for research use only.

Purity: Purified

Description: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Immunogen: Purified His-tagged protein was used to produced this monoclonal MGMT antibody.

Storage: Aliquot the MGMT antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.