Description
MGMT Antibody | F50325-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, FACS, WB, ELISA
Buffer: N/A
Limitation: This MGMT antibody is available for research use only.
Purity: Purified
Description: MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. This protein repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the protein is irreversibly inactivated.
Immunogen: A portion of amino acids 156-182 from the human protein was used as the immunogen for this MGMT antibody.
Storage: Aliquot the MGMT antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
