MGMT Antibody | F43302-0.4ML

MGMT Antibody | F43302-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IF, ELISA

Buffer: N/A

Limitation: This MGMT antibody is available for research use only.

Purity: Antigen affinity

Description: MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this MGMT antibody.

Storage: Aliquot the MGMT antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.