MGLL, His-tag, GST-tag | 71096

MGLL, His-tag, GST-tag | 71096 | Gentaur US, UK & Europe Disrtribition

Category: Metabolic Enzymes/Protein

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: Monoacylglycerol lipase (MAGL) catalyzes hydrolysis of intracellular triglyceride stores, forming fatty acids and glycerol. It is a key enzyme in the metabolism of 2-arachidonoylglycerol, hence is involved in a similar pathway to DAGL. MAGL is localized in the enteric nervous system where it functions to regulate levels of endocannabinoids, and as a result, regulates intestinal motility. It is also found in the gut epithelium where it may have a role in digestion.

Description: Human monoglyceride lipase (MGLL), GenBank Accession No. NM_007283, a.a. 2-313(end), with N-terminal His-tag and N-terminal GST-tag, MW=62 kDa, expressed in Sf9 insect cells via a baculovirus expression system.

Product Type: Protein

Shippement Condition: -80°C