Description
Melanoma Marker Antibody Cocktail (MART-1 & Tyrosinase & gp100) | V8328-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: DT101+ BC199 + T311 + HMB45
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Melanoma Marker antibody cocktail is available for research use only.
Purity: Protein G affinity chromatography
Description: This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Immunogen: Recombinant hMART-1 protein (DT101 & BC199), extract of pigmented melanoma metastases from lymph nodes (HMB45) and recombinant tyrosinase protein (T311) were used as the immunogen for this Melanoma Marker antibody cocktail.
Storage: Store the Melanoma Marker antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
