MeCP2 Antibody | F48099-0.08ML

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SKU:
800-F48099-0.08ML
Weight:
1.20 KGS
€644.00
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Description

MeCP2 Antibody | F48099-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, ELISA

Buffer: N/A

Limitation: This MeCP2 antibody is available for research use only.

Purity: Purified

Description: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this MeCP2 antibody.

Storage: Aliquot the MeCP2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

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Additional Information

Size:
0.08 mL
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