Description
MeCP2 Antibody | F41828-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, FACS, ELISA
Buffer: N/A
Limitation: This MeCP2 antibody is available for research use only.
Purity: Antigen affinity
Description: MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]
Immunogen: A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.
Storage: Aliquot the MeCP2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
