MeCP2 Antibody | F41828-0.08ML

MeCP2 Antibody | F41828-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, FACS, ELISA

Buffer: N/A

Limitation: This MeCP2 antibody is available for research use only.

Purity: Antigen affinity

Description: MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]

Immunogen: A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.

Storage: Aliquot the MeCP2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.