Description
MDM2 TR-FRET Assay Kit | 79773 | Gentaur US, UK & Europe Disrtribition
Category: Ubiquitination/Assay Kit
Application: Great for screening small molecular inhibitors for drug discovery and HTS applications.
Background: N/A
Description: Human Casitas B-lineage lymphoma proto-oncogene b (MDM2) is an E3 ubiquitin-protein ligase that functions as a negative regulator of T-cell activation. It is a potential drug target in cancer immunotherapy. The MDM2 TR-FRET Assay Kit is designed to measure MDM2 auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled ubiquitin and a terbium-labeled anti-GST antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.
Product Type: Assay Kit
Shippement Condition: -80°C
