Description
MCM3 Antibody | R30735 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P, ICC, IF, FACS
Buffer: N/A
Limitation: This MCM3 antibody is available for research use only.
Purity: Antigen affinity
Description: Minichromosome maintenance, S. cerevisiae, homolog of, 3, also called RLFB or P1 Protein, is a protein that in humans is encoded by the MCM3 gene. MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Immunogen: An amino acid sequence from the N-terminus of human MCM3 (REAQRDYLDFLDDEE) was used as the immunogen for this MCM3 antibody (100% homologous in human, mouse and rat).
Storage: After reconstitution, the MCM3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
