MBTPS2 Polyclonal Antibody | E-AB-52057

MBTPS2 Polyclonal Antibody | E-AB-52057 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, IHC, ELISA

Research Area: Cell Biology, Cardiovascular, Metabolism, Signal transduction

Background: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

Lead Time: 7~10 days

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human MBTPS2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:10-1:50, ELISA 1:5000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 57 kDa

Observed Molecular Weight: Refer to figures

Clonality: Polyclonal