MBD3 Antibody | RQ4821

MBD3 Antibody | RQ4821 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: AFEE-13

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This MBD3 antibody is available for research use only.

Purity: Affinity purified

Description: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The MBD3 gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. [RefSeq]

Immunogen: A synthetic peptide specific to human MBD3 was used as the immunogen for the MBD3 antibody.

Storage: Store the MBD3 antibody at -20 °C.