Description
Mavs Antibody (Ips-1) | F47745-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This Ips-1 antibody is available for research use only.
Purity: Antigen affinity
Description: Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
Immunogen: A portion of amino acids 1-30 from the mouse protein was used as the immunogen for this Ips-1 antibody.
Storage: Aliquot the Ips-1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.