Description
MART-1 / Melan-A Antibody | V2121-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: A103
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse, Rat
Application: FACS, IF, WB, IHC-P
Buffer: N/A
Limitation: This Melan-A antibody is available for research use only, not for diagnostic or therapeutic testing.
Purity: Protein G affinity chromatography
Description: Antibody A103 is specific for Melan-A (likely an abbreviation for 'melanocyte antigen'), also called MART-1, a unique antigen on melanoma cells recognized by CTLs (cytotoxic T lymphocytes), making it useful as a melanocyte differentiation marker. It is commonly used to identify metastatic tumors of melanocytic origin, as well as perivascular epithelioid cell tumors. Unlike another commonly used Melan-A / MART-1 antibody, M2-7C10, A103 also stains steroid hormone producing cells, making it valuable in identifying adrenocortical carcinomas.
Note: this protein was identified in 1994 by two different labs, one naming it MART-1 (melanoma antigen recognized by T-cells) and the other Melan-A. Both names are commonly used in literature, but clone A103 antibody is generally referred to as being anti-Melan-A.
Immunogen: Recombinant human protein was used as the immunogen for the Melan-A antibody.
Storage: Store the Melan-A antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
