MART-1 / Melan-A Antibody Cocktail | V3156-100UG

MART-1 / Melan-A Antibody Cocktail | V3156-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: M2-7C10 + M2-9E3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: FACS, IF, WB, IHC-P

Buffer: N/A

Limitation: This Melan-A antibody cocktail is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Immunogen: Recombinant human protein was used as the immunogens for this Melan-A antibody cocktail.

Storage: Store the Melan-A antibody cocktail at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).