MAPKAPK3, GST-tag | 40117
- SKU:
- 412-40117
Description
MAPKAPK3, GST-tag | 40117 | Gentaur US, UK & Europe Disrtribition
Category: Kinase-Serine/Threonine/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: MAPKAPK3 is closely related to MAPKAPK2 sharing 72% nucleotide and 75% amino acid identity (1). MAPKAPK3 is activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of MAPKAPK3 as an integrative element of signaling in both mitogen and stress responses (2).
Description: Recombinant human MAPKAPK3, full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
Product Type: Protein
Shippement Condition: -80°C
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