Description
Major Vault Protein Antibody / MVP | F54845-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC-P, FACS, WB
Buffer: N/A
Limitation: This Major Vault Protein antibody is available for research use only.
Purity: Purified
Description: MVP, the major vault protein, is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance.
Immunogen: A portion of amino acids 863-893 from the human protein was used as the immunogen for the Major Vault Protein antibody.
Storage: Aliquot the Major Vault Protein antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.