Description
LOXL4 Antibody | F45468-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This LOXL4 antibody is available for research use only.
Purity: Antigen affinity
Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Immunogen: A portion of amino acids 575-603 from the human protein was used as the immunogen for this LOXL4 antibody.
Storage: Aliquot the LOXL4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
